Oxidative hemolysis of erythrocytes

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Oxidative Hemolysis of Erythrocytes Induced by Various Vitamins

Hemolytic effect of some water-soluble vitamins (niacin B5, pyridoxine B6, thiamine B1 and ascorbic and acid C) on erythrocytes was studied spectrophotometrically at relatively high concentration. The oxidation mechanism of hemoglobin was the same for the used vitamins. Vitamin C was the strongest hemolytic agent in comparison with the other vitamins, while vitamin B1 is the weakest one. The re...

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Hemolysis of Erythrocytes in Contact with Glass

1. Washed erythrocytes, in both acid and alkaline solutions, hemolyze more rapidly when allowed to settle out on a clean microscope slide than when kept in suspension. 2. This is also true on slides coated with paraffin, paraffin oil, or vaseline, and on mica surfaces. 3. The presence of as little as 0.1 per cent serum inhibits such contact hemolysis, particularly in alkaline solutions. 4. Cont...

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Gadolinium (Gd), an element that possesses a character similar to that of calcium or magnesium, is known to have a strong hemolytic effect on erythrocytes (RBC) at even very low concentrations. 3, 5 One of the major characteristics of sickle cell disease is hemolysis of the abnormal RBC. Therefore, concerns have been raised that Gadolinium, as an MRI contrast agent for clinical use, should not ...

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ژورنال

عنوان ژورنال: Biochemistry and Molecular Biology Education

سال: 2006

ISSN: 1470-8175,1539-3429

DOI: 10.1002/bmb.2006.494034062681